The rapid and pervasive spread of mis- and disinformation across the globe threatens to erode our information ecosystems and disrupt progress on the Sustainable Development Goals (SDGs). A team of five master’s students at Columbia University’s School of International and Public Affairs (SIPA) and their faculty advisor produced this report on different interventions by the UNDP Accelerator Labs aiming to use local solutions to tackle the problem of online mis- and disinformation in their specific countries. The report includes recommendations on the role of the United Nations and UNDP in combating mis- and disinformation in the Global South, as well as guidance for building effective partnerships to address its spread.